The coronary no-reflow phenomenon: a review of mechanisms and therapies

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The coronary no-reflow phenomenon: a review of mechanisms and therapies.

The phenomenon of no-reflow is defined as inadequate myocardial perfusion through a given segment of the coronary circulation without angiographic evidence of mechanical vessel obstruction. Temporary occlusion of the artery, a prerequisite condition for no-reflow, may be produced in the experimental setting or occur during reperfusion of an infarct-related artery or following percutaneous coron...

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No-reflow phenomenon.

To the Editor: In reviewing no-reflow, Rezkalla and Kloner1 indicted injuryinduced microvascular changes, but did not mention spasm of resistance vessels, which might be the basic mechanism of no-reflow. I proposed in 1971 that no-reflow (“stasis”) is due to ischemic injury-induced spasm, and the evidence seemed convincing.2 Short coronary occlusions reversed no-reflow, and this was interpreted...

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Demonstration of the "no-reflow" phenomenon by digital coronary arteriography.

6. Kennedy JW, Ritchie JL, Davis KB, Fritz JK. Western Washington rondomized trio1 of intracoronory streptokinase in acute myocordiol infarction. N Engl J Med 1983;309:1477-1482. 7. Schuler G. Schwarz F, Hofmann M, Mehmel H, Manthey J, Maurer W, Rauch B, Herrmann HJ, Kubler W. Thrombolysis in acute myocordiol injarction using intracoronary streptokinose: assessment by thallium-201 scintigraphy....

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'No-reflow' phenomenon.

A 57-year-old man presented with new anginal symptoms nine years after three-vessel coronary artery bypass grafting. Cardiac catherization revealed severely and diffusely diseased saphenous vein graft to the obtuse marginal coronary artery. Percutaneous coronary intervention was complicated by the ‘no-reflow’ phenomenon. The patient suffered a periprocedural myocardial infarction (peak troponin...

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The no reflow phenomenon in the coronary arteries.

In the last twenty years, the treatment of coronary heart disease with cardiac catheterization has greatly advanced. This therapeutic approach has had unexpected side effects, however, for which solutions must be found, particularly in the are of interventional cardiology. The “noreflow” phenomenon, a side effect, is an uncommon and critical occurrence and, if not reversed, causes a high rate o...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2001

ISSN: 0195-668X

DOI: 10.1053/euhj.2000.2172